Sekeres agreed that further research is needed to determine if certain cancers elevate the level of B12 in the body, or if the results of the study were completely confounded by the study’s design. Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. High B12 levels in the blood can be the result of liver disease, kidney failure and blood cancers. The blood levels of B12 and Folic Acid can be misleading. To give me peace of mind more than anything, he ordered blood work for several cancer markers. Coffee may help prevent prostate cancer, heart risk for men with breast cancer, and more cancer news from January 2021. “Think in real-time,” said Mikkael Sekeres, MD, MS, director of the leukemia program at Cleveland Clinic. Will you develop antibodies if you’re immunosuppressed? Higher than normal levels of Vitamin B12 may indicate cancer risk. Journal of the National Cancer Institute. Content on this website is for information only. Elevated plasma vitamin B12 has been associated with an increased cancer risk. This large cohort study shows that cancer patients with high B12 have increased mortality. High b12 levels and cancer. Vitamin B12 is an essential nutrient, important in nerve and blood cell health, and most people obtain enough of it in food. Consuming large quantities does not cause side effects or high levels in your system, whether you … At any rate, everyone agreed that while the results are curious, they’re not a reason to stop taking your multivitamins. A June 2013 review article published in the "Quarterly Journal of Medicine" reported that high vitamin B12 levels most commonly occur with liver cancer. The researchers found that the patients with the highest vitamin B12 levels also had the highest risk of being diagnosed with cancer, particularly in the first year after having the vitamin measurement taken. These patients did not have cancer when the researchers began tracking them, but they had been referred to have their vitamin B12 levels tested. Elevated plasma vitamin B12 has been associated with an increased cancer risk. resulting supplements would elevate their B12, Cancer News Digest: The Latest Developments in Cancer Research and Treatment for February 2021, The COVID-19 Vaccines and Cancer: What You Need to Know, Cancer News Digest: The Latest Developments in Cancer Research and Treatment for January 2021, Cancer News Digest: The Latest Developments in Cancer Research and Treatment for December 2020, Cancer News Digest: The Latest Developments in Cancer Research and Treatment for May 2020, Society for Immunotherapy of Cancer 2020: Pushing the Boundaries of Cancer Treatment, ‘Jeopardy!’ Host Alex Trebek Dies After Pancreatic Cancer Diagnosis. Hematologic disorders like chronic myelogeneous leukemia, promyelocytic leukemia, polycythemia vera and also the hypereosinophilic syndrome can result in elevated levels of cobalamin. But don’t throw out your supplements yet — the researchers theorize it’s more likely cancer causes high levels of B12 than B12 causing cancer. Causes of vitamin B12 deficiency include: Not enough vitamin B12 in diet (rare, except with a strict vegetarian diet) Diseases that cause malabsorption (for example, celiac disease and Crohn disease) Lack of intrinsic factor, a protein that helps the intestine absorb vitamin B12 Since B12 is a water-soluble vitamin, it’s generally considered safe, even at high doses. Elevated plasma vitamin B12 has been associated with an increased cancer risk. The risks were particularly elevated for liver cancer, pancreas cancer, and myeloid malignancies among persons with elevated B12 levels. High levels of B12 in the blood are linked to 15 per cent increased risk of lung cancer, according to a major international study.That's one more reason to stop buying supplements and eat a healthy, varied diet, researchers say. An elevated vitamin B12 level can be a nonspecific indicator of several types of solid organ cancer. No Tolerable Upper Intake Level (UL) has been established for B12, due to its low level of toxicity. Carcinomas most frequently involved are HCC and metastatic colon, breast and pancreatic cancer. The results take about 3 weeks so I have to be patient. An elevated vitamin B12 level can be a nonspecific indicator of several types of solid organ cancer. Views expressed here do not necessarily reflect those of ScienceDaily, its staff, its contributors, or its partners. If elevated, it does not automatically mean you should stop taking all B vitamins. Vitamin B12 is an essential nutrient, important in nerve and blood cell health, and most people obtain enough of it in food. A high level indicates a true B12 deficiency. This association was independent of cancer stage, comorbidity, age and sex. Hematologic disorders like chronic myelogeneous leukemia, promyelocytic leukemia, polycythemia vera and also the hypereosinophilic syndrome can result in elevated levels of cobalamin. Chiche et al. The Answer Might Lie in Knowing What Doesn't Work, New Study Gives the Most Detailed Look Yet at the Neuroscience of Placebo Effects, Real-Time Dialogue With a Dreaming Person Is Possible. Vitamin B-12 (cobalamin) is a water-soluble vitamin that plays essential roles in red blood cell formation, cell metabolism, nerve function and the production of DNA.Food sources of vitamin B-12 include poultry, meat, fish and dairy products.